In 2006, at the University Hospital (CHU) of Toulouse, the AMA project was born (Assistance Médicale Ambulatoire, or outpatient medical support). Objectives: to assess the effectiveness of telephone follow-up in improving onco-haematology patients’ compliance with dose intensity. Seven years later, the project has show very positive results, with an average dose reduction of 8%, compared to 20% without follow-up – all due to a simple and inexpensive procedure.
In 2015, Prof. Laurent, encouraged by these achievements, suggested duplicating the study in Ivory Coast, where nearly 20,000 new cancer cases are reported annually, with a 60% treatment refusal and dropout rate, and a 20% survival rate at five years. The project, financed by Fondation Pierre Fabre, took the new name AMAFRICA. A simple, monocentric, randomised study will be conducted in collaboration with the onco-haematology department at the Abidjan University Hospital, headed by Professor Koffi. The central hypothesis is that consistent telephone contact with the patient by a coordinating nurse could reduce the dropout rate (primary objective), but also help identify and prioritise the causes of treatment dropout (secondary objective).
The AMA procedure seems well-suited to the challenge of monitoring Ivorian patients, as 60% of the local population has a mobile phone. Working with a group of 100 adults and children with lymphoma, AMAFRICA will make it possible to track patients in the active phases of their treatment, and compare treatment adherence and toxicity in regard with patients not receiving phone follow-up during treatment.
*Total dose administered and administration rate.